Subsonic 4.6 running on a Highly Available Hyper-V VM, with Windows Server "8" (2012) Beta Datacenter as the guest OS. Hosts are a pair of identical servers, 8 cores @ 3.2Ghz each, 32GB RAM, 2 60GB SATAIII SSDs in Raid 1, with storage on a custom built 20 disk Raid 6 array (currently at 22TB, more drives to come). VMs also stored on the storage array, managed by Microsoft System Center 2012 Virtual Machine Manager.
Storage array utilizes NIC teaming with 4 gigabit NICs, aggregated to my gigabit switch. Each VM host server utilizes 3 NICs, 2 NICs teamed to the switch, and 1 NIC to the DMZ network. 50mb down/5mb up WAN connection, across my Untangle firewall.
On the VM with SubSonic, I also run bliss to manage my album artwork (I prefer it to be embedded), read this post about it if interested:
http://deviantengineer.com/?p=168Lastly, I also run Plex Media Server for media serving to my Logitech Revue (running Android 3.2).
SubSonic works amazingly well with UNC paths. So happy about that.